Journal article
Infrared Based Saliva Screening Test for COVID‐19
Bayden R Wood, Kamila Kochan, Diana E Bedolla, Natalia Salazar‐Quiroz, Samantha L Grimley, David Perez‐Guaita, Matthew J Baker, Jitraporn Vongsvivut, Mark J Tobin, Keith R Bambery, Dale Christensen, Shivani Pasricha, Anthony K Eden, Aaron Mclean, Supti Roy, Jason A Roberts, Julian Druce, Deborah A Williamson, Julie McAuley, Mike Catton Show all
Angewandte Chemie | Wiley | Published : 2021
Abstract
AbstractSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has resulted in an unprecedented need for diagnostic testing that is critical in controlling the spread of COVID‐19. We propose a portable infrared spectrometer with purpose‐built transflection accessory for rapid point‐of‐care detection of COVID‐19 markers in saliva. Initially, purified virion particles were characterized with Raman spectroscopy, synchrotron infrared (IR) and AFM‐IR. A data set comprising 171 transflection infrared spectra from 29 subjects testing positive for SARS‐CoV‐2 by RT‐qPCR and 28 testing negative, was modeled using Monte Carlo Double Cross Validation with 50 randomized test and model sets. The tes..
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Grants
Awarded by Australian Nuclear Science and Technology Organisation
Awarded by Australian Research Council
Awarded by Faculty of Science, Monash University
Awarded by National Health and Medical Research Council